Media and Feed Strategies – Monoclonal Antibody Production

The cell line manufacturing technology that drives the Selexis Media and Feed Strategies comprises two major elements:

SUREfeed Strategy

The Selexis SUREfeed Strategy defines the media, seeding, and feeding parameters for Selexis’ suspension-adapted CHO-K1 production lines in both shake flasks, allowing for faster and more efficient scale-up to large bioreactors. Media optimization is already done, saving Selexis partners massive amounts of time and money. With the Selexis SUREfeed Strategy, Selexis is typically able to achieve 2-7 g/L monoclonal antibody production level in shake flasks.

Off-the-shelf media and off-the-shelf feed

The SUREtechnology Platform utilizes animal-derived, component-free, chemically defined (CD), off-the-shelf media and feeds and is commercially available from multiple suppliers.