January 4, 2012 | BioProcess International

Rapid Production of Functional Proteins of a Combinatorial IgG Library in CHO Cells

Recombinant DNA (rDNA) technologies provide a wide range of tools for producing a broad array of recombinant proteins. Since the early 1970s, the biotechnology industry has harnessed those tools — together with genetic engineering and genomics — for developing new classes of innovative and effective therapeutic molecules. The therapeutic recombinant protein market segment now represents the core of the medical biotechnology industry, with hundreds of companies involved in discovery, development, and marketing…

David Calabrese, Valerie LeFourn, Pierre-Alain Girod, Alexandre Regamey, Aline Claude, Armelle Gaussin and Igor Fisch