Research Cell Bank Development
September 29, 2017
The development of stable, high-producing, clonal cell lines requires advanced technologies that address the individual expression and secretion needs of each protein as well as the production demands required of research cell banks (RCB). The SUREtechnology Platform™ is uniquely positioned to meet this breadth of...
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Lead Identification
August 14, 2017
Pick the Best Candidate for Improved Clinical Success Cells used for drug development are critically important in almost every aspect of biologic drug discovery, development  and manufacturing. The Selexis SUREtechnology Platform™, which is well-established as a fast and cost effective approach for generating manufacturing cell lines,...
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Secretion Bottlenecks
August 14, 2017
With certain recombinant proteins, optimal expression cannot be achieved by elevated transcription alone. Low productivity can be the result of a myriad of issues including faulty cleavage and protein precipitation, improper folding, metabolic overload, or backlog in protein translocation or vesicle trafficking. Within each of...
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Designer CHO Cell Lines | Detailed Regulatory Packages
August 13, 2017
Expression of an exciting new therapeutic minibody was hitting a production bottleneck. The minibody gene was readily transcribed using the Selexis SUREtechnology Platform™, however, the high levels of transcription did not translate into high productivity levels. Detailed evaluation of the cell line determined that one of...
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